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Aesthetic mesotherapy: the origin of FILORGA Laboratories

Aesthetic mesotherapy, the origin of FILORGA know-how

In anti-aging aesthetic medicine, mesotherapy is the basic technique for improving skin quality in order to have more beautiful skin for longer. Indeed, to radiate and breathe good health, it is necessary to maintain our cells by giving them the essential elements to function properly. Without these contributions, all other actions and treatments will be less effective.

In this article, we reveal everything you need to know about this technique and explain how FILORGA was inspired to create N.C.E.F. [NEWCELLULARENCAPSULATEDFACTORS], our signature ingredient.


The essentials of aesthetic mesotherapy in a few lines

  • Mesotherapy was invented in 1952 by a French doctor to treat joint and muscle pain.
  • This technique was later used for aesthetic purposes, notably by Dr. Michel Tordjman, founder of Laboratoires FILORGA.
  • The principle of mesotherapy is simple: using a needle, the The doctor injects a revitalizing solution directly into the area to be treated.
  • The N.C.E.F. [New Cellular Encapsulated Factors] is the star complex of FILORGA Laboratories. It contains the iconic ingredients of aesthetic mesotherapy.


The History of Aesthetic Mesotherapy

Originally, mesotherapy sessions for pain relief

The first mesotherapy techniques, from the Greek mesos, meaning "in the middle" and 400;">therapeia “cure,” were developed in 1952 by French physician Michel Pistor. Seeking an alternative to taking painkillers to relieve rheumatism, a practice often accompanied by unpleasant side effects, he came up with the idea of ​​minimizing the distance between the treatment and the painful area.

His motto was "Little, rarely, and in the right place," and his technique consisted of injecting low doses of medication directly into the painful area (to quote a famous advertisement). An immediate success, Dr. Pistor's method was quickly adopted by the medical world.

Today, mesotherapy is still widely used to treat conditions such as:

  • Tendinopathies, such as those of the knee, elbow, and shoulder.
  • Muscle contractures and pain.
  • Periostitis.
  • Early osteoarthritis and of courserheumatism.

Its main advantages are:

  • A minimally invasive medical technique with superficial injections into the skin.
  • Rapid effectiveness on pain and inflammation.
  • A treatment that does not require oral anti-inflammatory medication.
  • For athletes,a reduction in downtime.

Mesotherapy injections are generally well tolerated, with no bothersome side effects and no contraindications other than possible intolerances or allergies to the products.


The emergence of mesotherapy for aesthetic purposes

It was at the end of the 1970s that the spectrum of mesotherapy expanded with the first revitalizing injections conceived by Dr. Tordjmann (we will return to this major advance in aesthetic medicine a little later). The injected products are no longer just painkillers, but skin biostimulators.

These active ingredients are those found today in cosmetic products: non-crosslinked hyaluronic acid, vitamins,antioxidants, collagen boosters, amino acids, growth factors, etc. They serve to stimulate skin cells to revitalize the skin and improve its tone, evenness, and radiance.

The Benefits of Cosmetic Mesotherapy on Skin Quality

Before delving into the technical details, a little clarification is necessary. Many terms are used to describe cosmetic mesotherapy: revitalizing injections, biostimulation, skin boosters, mesolift, to name a few. It could be confusing, but know that all these expressions actually mean THE SAME THING. But what exactly is "good skin quality"? It's primarily what you see and feel every day. Skin quality means a radiant, even complexion, visibly hydrated, supple, and toned skin, with a smooth texture and reduced wrinkles. It's the expression of healthy skin, radiating vitality and displaying a youthful, rested appearance.

The principle of aesthetic mesotherapy aims to achieve this ideal.

It's always about delivering the active substances mentioned above to the skin directly where they need to act. These ingredients will stimulate fibroblasts, the dermal cells that produce collagen, elastin, andhyaluronic acid. The most frequently treated areas are the face, décolleté, hands, and neck.

Thanks to these targeted applications, and depending on the active ingredients used by practitioners, microinjections:

  • Preventskin aging.
  • Improve skin quality and give it a boost of radiance.
  • Deeply moisturize and plump.
  • Smoothes fine lines and wrinkles.
  • Helps fight acne, stretch marks, and hair loss.

Dr Tatiana Gonçalvez Pereira

"Revitalizing injections, known as mesotherapy, are a common practice in aesthetic medicine. They are used when the aim is to restore and revitalize the skin, provide it with hydration, tone, and improve its quality. »

Dr. Tatiana Gonçalvez Pereira

[Portugal]⁽¹⁾

How many mesotherapy sessions does it take to see results? ?

A complete protocol generally requires3 to 5 sessions spaced 2 to 3 weeks apart. Results are visible after 2 or 3 sessions and must be maintained with a new microinjection every 6 months to 1 year. Aesthetic doctors have three techniques at their disposal, which vary depending on: The way the needle penetrates the skin, which will influence the injection depth. The way the product is applied, either continuously in a single pressure or drop by drop to form small reservoirs. a nutrient cocktail from which cells draw according to their needs.

Importantly, people of all ages can use revitalizing injections.

The N.C.E.F. includes the same active ingredients as those used in aesthetic mesotherapy

The links between FILORGA and aesthetic mesotherapy

Behind FILORGA Laboratories, there is a pioneer: Dr. Michel Tordjman. A French physician passionate about cellular biology, he became interested in skin regeneration early on, convinced that good skin quality is the key to beauty. In 1978, he developed an innovative injectable solution used in aesthetic mesotherapy, composed of ingredients naturally present in the skin. His goal: to improve skin quality by stimulating cell regeneration mechanisms. It is based on regenerative science, which aims to restore impaired biological functions in order to revitalize cells and stimulate their activity. With its mesotherapy injections, it lays the foundations for aesthetic medicine focused on revitalization, prior to any targeted intervention. Initially reserved for healthcare professionals, this approach inspired the creation of FILORGA, the first French aesthetic medicine laboratory founded in 1978. With a strong ambition: to offer daily support to its patients at home. FILORGA Laboratories have thus developed an advanced cosmetic range, with the common ingredient: the N.C.E.F. complex, designed from the same active ingredients as those found in Dr. Tordjman's injections. span>

N.C.E.F., a concentrate of innovation for skin quality

The latest-generation N.C.E.F. complex from Filorga revitalizes cells and provides them with energy and the elements they need to ensure their repair, protection, and vitality.


This complex, exclusive to Laboratoires FILORGA, includes:

  • Hyaluronic acid.

  • Amino acidsvitamins.

  • minerals.

  • Acoenzyme.

  • Anantioxidant.

All these ingredients are essential for the proper functioning of cellular metabolism and are known for their ability to improve hydration, radiance, skin firmness and density.

For targeted action,FILORGA experts have developed a cutting-edge encapsulation technique: the active ingredients are contained in multi-lamellar liposomes, inspired by cell membranes,capable of diffusing them into the heart of the epidermis.This technology increases the bioavailability of the ingredients, improves their stability, and reduces the risk of irritation. It enables a targeted, progressive, and lasting action, comparable to that of injections.



The NCEF-REVITALIZE range, inspired by mesotherapy injections

N.C.E.F. is present in all FILORGA treatments. Among them, the NCEF-REVITALIZE range was designed for tired skin seeking overall revitalization and a visible improvement in skin quality.

  • NCEF-REVITALIZE Serum: this ultra-concentrated serum acts as a true cellular booster. It significantly improves skin firmness, radiance, and texture. href="https://fr.filorga.com/collections/ncef/products/ncef-reverse-eyes?variant=49477969936681">

  • NCEF-REVITALIZE Mask: This infused sheet mask provides an immediate radiance boost and deep hydration, ideal as a treatment or express treatment.

  • With the NCEF-REVITALIZE range, FILORGA offers the science of Mesotherapy encapsulated in a complete routine to brighten, smooth, and firm.


    (1) Original testimonial in Spanish, translated into French by an artificial intelligence tool. (2) Excluding cleansers, sheet masks, and TIME-FILLER SHOT 5XP. (3) Instrumental measurement - 32 women - Results after 7 days of twice-daily application of NCEF-REVITALIZE serum. p<0.05 (4) Clinical scoring - 32 women - Results after 28 days of twice-daily application of NCEF-REVITALIZE serum. p<0.05 (5) Image analysis - 32 women - Results after 28 days of twice-daily application of NCEF-REVITALIZE serum. p<0.001